The 10 billboards in locations such as Vauxhall Cross and Cromwell Road will be operational from September. The size of standard 48 sheets, they will be controlled from a central hub, allowing ads to be updated instantly so that advertisers can target day-parts.
Unlike the LED screens already used by Clear Channel in the US, the new screens use energy-efficient "reflective technology". The surfaces capture reflected light to display the ad - sunlight during the day and front lights at night.
Unlike LED screens which tend to be washed out in bright sunlight, reflective screens look brighter in strong light.
"The screens will provide unparalleled flexibility, enabling advertisers to target audiences at different times of day, in different mindsets and with different messages," said Clear Channel UK's interim chief executive Barry Sayer.
The company is looking to sign one-year contracts with five advertisers and one traffic news provider. Sayer said the company had received interest from the US as well as the UK, but it initially wanted to work with clients in the local market.
Ads will typically be five seconds long and shown simultaneously across the network - giving each advertiser an estimated 19 thousand ad displays a week. The boards are priced at 90p per five-second slot across 10 units.
The five seconds have been calculated according to dwell time of traffic next to sites, ensuring that passing cars would see all the ads in a loop.