The show, presented by Aggie MacKenzie and Kim Woodburn, returns on April 28 for a 10-week run. It is the first time the show has been sponsored.
Cif will showcase all three of its sub-brands - Cif Cream, Cif Oxy-Gel and Cif Bathroom - in the sponsorship. Three separate programme credit executions are being created by Mustoes to show the versatility of the brand around the house.
The deal was negotiated between Channel 4 and sponsorship specialist Malcolm Grant Associates.
Press and radio advertising will support the sponsorship, alongside dedicated roadshows, on-pack competitions, door-drops and in-store promotions.
The deal marks Cif's second use of TV sponsorship. Last May it agreed a 12-month six-figure deal to sponsor UK Style's daytime homes schedule to showcase its Oxy-Gel product.