The ad, which features a litany of disabled athletes and performers doing extraordinary things, has generated 1.26 million shares across social media since its release on 14 July.
According to data from Unruly, "We’re the superhumans" is the second-most-shared ad of all time, behind Procter & Gamble’s "Best job" ad in 2012 which has been shared 2.45 million times.
The Channel 4 ad, promoting its coverage of this year’s Paralympic Games in Rio de Janeiro, is well ahead of the second-most-shared ad this year, Under Armour’s "Rule yourself" featuring American swimmer Michael Phelps, which has had 308,00 shares.
P&G, whose spots have topped Unruly’s most-shared charts at the last two Summer and Winter Olympics, currently holds fourth, with its "" video attracting 180,725 shares.
Nike was the only advertiser to have two videos in the top 10, with "" and "" in 7th and 10th respectively.
The longest ad in the top 10 list comes from Gatorade, which released a 7+ minute cartoon titled "", highlighting the story of track and field superstar Usain Bolt. The video is 8th on the list after attracting 63,803 shares so far.
Top 10 most shared Olympics 2016 ads
1. Channel 4: "We're the Superhumans | Rio Paralympics 2016 trailer" (1,256,567 shares)
2. Under Armour: "Rule yourself | Michael Phelps" (308,000 shares)
3. Under Armour "Rule yourself | USA womens gymnastics" (186,865 shares)
4. P&G "Thank you, yom - Strong | Rio 2016 Olympic Games" (180,725 shares)
5. BBC Sport "Rio 2016 Olympic Games: trailer" (79,295 shares)
6. United "Team USA commercial: 'One journey. Two teams.'" (72,355 shares)
7. Nike "Unlimited Serena Williams" (65,668 shares)
8. Gatorade "The boy who learned to fly | Usain Bolt" (63,803 shares)