The initiative aims to give people breaks in comedy, drama, news and documentaries via the broadcaster's key channel.
Over 25 years, names such as Ewan McGregor, Harry Enfield and Simon Pegg have started their career on the channel and Julian Bellamy, head of Channel 4, is hoping more will follow them.
Bellamy said: "We thought it would be tremendously exciting and creatively refreshing to provide this opportunity on a major scale to a wide range of inspired newcomers.
"It's an enormous risk for a major TV channel and one that only Channel 4 would take."
The first programme to run in the season will be stand-up and sketch series 'Tonightly', beginning on August 1.
Teen soap 'Hollyoaks' will also lend itself to the cause on August 29 with an episode written by Jamie Austin, who was chosen among more than 300 entrants in a scriptwriting competition.
Budding film directors and writers get their turn in the last week of the month when a series of seven new films will be shown, featuring actors including Alfie Allen and Imelda Staunton.
Channel 4 News will broadcast four films reported or produced by new journalists.
In documentaries, the 'First Cut' strand showcasing up-and-coming directors returns with a run of 12 30-minute programmes, with the full run of 20 films airing on More4.
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