One poster features a condom opposite the teat of a baby's drinking bottle with the headline -- "It's your choice". Another poster positions the condom against a pregnancy test kit.
The outdoor activity will be supported by press and internet ads.
Simon Blake, Brook's chief executive, said: "Some people won't be comfortable with an outdoor poster that has such a frank tone and message as well as a huge condom on it. We want the campaign to start conversations among adults and young people.
"We cannot allow generation after generation to grow up without the information they need to manage and enjoy their sexual health. Eye-catching, arresting campaigns such as this one is just one of many ways that Brook intends to support the young."
This is the first major advertising campaign Brook has launched and the first campaign that Feel has produced for the charity since winning the account in December.
Chris Arnold, creative partner at Feel, said: "We are expecting to draw complaints from middle-aged, middle England. We're telling it as it is; this is blunt honest advertising with no PC softening of the message. People have a choice."
Brook will be developing the "It's your choice" campaign theme throughout the year with different creative executions highlighting the different sexual health choices that people have.
The campaign will be launched and supported by singer and writer Mica Paris, who acts as Brook's ambassador.