Launched today, users will be able to download shows to their PlayStation Portable, and other mobile devices that have wi-fi capability, free of charge for a two-month trial period.
The deal is set to coincide with tonight's launch of Celebrity Big Brother, which will be the subject of some programmes on 4Radio.
The aim of the partnership is to enable 4Radio to target morning commuters, creating a form of breakfast show for people who make use of The Cloud's network of 7,500 wifi hotspots located in high footfall places such as coffee shops, hotels and airports.
As soon as users log on to the internet they will be automatically directed to a landing page with a link to a branded Cloud/4Radio portal where they will be able to download programmes such as Morning News, Celebrity Big Brother and music show SlashMusic.
Nathalie Schwarz, director of Channel 4 Radio, believes the deal with Cloud will enable 4Radio to target listeners who want "bold and mischievous radio programming" but whose busy lifestyles mean they do not have time to tine in before they leave home.
According to Niall Murphy, chief technology officer at The Cloud, wi-fi usage is starting to shift from business to consumer devices and by the end of this year 80% of wi-fi enabled devices are expected to be targeted at consumers.